GiraffeIT.com was called into a site to help diagnose some GPO not working quite how they were expecting.
Long of the short is a locally cached copy of the profile was being stored on the local machines. There are a few settings you can use in Windows 2008R2 to prevent the cached copy staying on the machine for more than x days. However for completeness I wanted the profiles gone there and then. Cue DelProf2. ( available here ) A few tweaks and a rough and ready batch file called via a startup trigger in a GPO and voila. No more cached local profiles at machine turn on.